Programming Services



Biological Databases


In the current omics era, biological databases are indispensable for the management and storage of biological and biomedical data, especially those related to NGS projects. At Biotechvana we have an excellent team of programmers specialized in the development of biological databases, intranets, wikis, servers, and web resources, for both the academy and the industry, adapting our developments to any need and/or idea or requirement of our customers.

We would be delighted to realize your web project or database by providing you with the following services:

  • Dynamic web programming based on most common Frameworks and CMS
  • Development and implementation of back-end infrastructures using Apache, Java, PHP, and MySQL
  • Front-end development of web interfaces for querying the database
  • Migration and/or conversion of databases
  • Implementation of containers (dockers)
  • CyberSecurity and assessment in legal requirements
  • Graphic and corporate design of the web resource or database
  • Domain administration, hosting, and housing
  • Technical support for use and management
  • Infrastructure maintenance and updating service
  • Storage services (backups) and restoration of lost data
  • Dissemination on social networks and SEO services

Tailor-made software and pipelines


Our team also has wide experience in software development using different languages such as C#, C++, Java, PHP, Python, Perl, R, and more. If you are looking for customized software for your research, our programming team would be happy to provide you with information on our quotes in developing tailor-made applications.

Some of our most demanded services are:

The cost of our programming solutions may vary depending on the software or database project. If you are interested in getting more information about it, please contact us at biotechvana(at)biotechvana.com and we will be glad to organize a personalized meeting with you in order to discuss and evaluate your specific project.

Related publications



  • Hafez A and 17 co-authors (including Soriano B, Ceprian R, Elsayed. AA, MArtinez G, and llorens C). 2022. RNASeq and VariantSeq applications and Server Side of GPRO suite. ArXiv https://arxiv.org/abs/2202.07473
  • Martinez-Gonzalez B and 24 co-authors (including llorens C and Soriano B). 2022. SARS-CoV-2 Point Mutation and Deletion Spectra, and Their Association with Different Disease Outcome. BioRxiv.https://doi.org/10.1101/2022.01.10.475768
  • Gomez-Gonzalez A, Zamora I, Soriano B, Llorens C. 2022. Prototipo de servidor web para el análisis bioinformático de datos de citometría de flujo. BiBi Software Article: 2022-SOFT1, ISSN 1988-7957. https://bioinformatics.biotechvana.com/index.php/article/40
  • Baquero F, Campos M, Llorens C, Sempere JM. 2021. P systems in the time of COVID-19. J. Membr. Comput. doi: https://doi.org/10.1007/s41965-021-00083-1
  • Campos M, Sempere JM, Galán JC, Moya A, Llorens C, de-los-Angeles C, Baquero-Artigao F, Cantón R, Baquero F. 2021. Simulating the impact of non-pharmaceutical interventions limiting transmission in COVID-19 epidemics using a membrane computing model, microLife, Volume 2, 2021, uqab011. doi: https://doi.org/10.1093/femsml/uqab011
  • Hafez A, Futami R, Arastehfar A, Daneshnia F, Miguel A, Roig FJ, Soriano B, Perez-Sánchez J, Boekhout T, Gabaldón T, Llorens C. 2020.SeqEditor: an application for primer design and sequence analysis with or without GTF/GFF files, Bioinformatics, 37(11), 1610-1612 https://doi.org/10.1093/bioinformatics/btaa903
  • Campos M, San Millan A, Sempere JM, Lanza VF, Coque TM, Llorens C, Baquero F. 2020. Simulating the Influence of Conjugative Plasmids Kinetic Values on the Multilevel Dynamics of Antimicrobial Resistance in a Membrane Computing Model. Antimicrobial Agents and Chemotherapy May 2020, AAC.00593-20 http://dx.doi.org/10.1128/AAC.00593-20
  • Hovhannisyan H, Hafez A, Llorens C, Gabaldon T. 2020. CROSSMAPPER: estimating cross-mapping rates and optimizing experimental design in multi-species sequencing studies. Bioinformatics. 36(3): 925-927 https://doi.org/10.1093/bioinformatics/btz626
  • Fouad MM, Hafez A, Hassanien AE. 2019. Optimizing topologies in wireless sensor networks: A comparative analysis between the Grey Wolves and the Chicken Swarm Optimization algorithms. Computer Networks 163, 106882. https://doi.org/10.1016/j.comnet.2019.106882
  • Pérez-Sánchez J, Naya-Català F, Soriano B, Piazzon MA, Hafez A, Gabaldón T, Llorens C, Sitjà-Bobadilla A, Calduch-Giner J. 2019. Genome Sequencing and Transcriptome Analysis Reveal Recent Species-specific Gene Duplications in the Plastic Gilthead Sea Bream. Front. Mar. Sci. 20 https://doi.org/10.3389/fmars.2019.00760
  • Campos M, Capilla R, Llorens C, Canton R, Moya A, Sempere JM, Coque T, Fernandez-Lanza V, Naya F, Futami R, Baquero F. 2019. Simulating multilevel dynamics of antimicrobial Resistance in a membrane computing Model. MBio 10(1),e02460-18 https://doi.org/10.1128/mBio.02460-18
  • Baquero F, Campos M, Llorens C, Sempere JM. 2018 A Model of Antibiotic Resistance Evolution Dynamics Through P Systems with Active Membranes and Communication Rules. Enjoying Natural Computing pp 33-34. https://link.springer.com/chapter/10.1007/978-3-030-00265-7_3
  • Saus E, Willis JR, Pryszcz LP, Hafez A, Llorens C, Himmelbauer H, Gabaldon T. 2018. nextPARS: Parallel probing of RNA structures in Illumina. Published in Advance January 22, 2018, RNA doi: 10.1261/rna.063073.117
  • Campos M, Llorens C, Sempere JM, Futami R, Rodríguez I, Carrasco P, Capilla R, Latorre A, Coque TM, Moya A AND Baquero F. 2015. A membrane computing simulator of trans-hierarchical antibiotic resistance evolution dynamics in nested ecological compartments (ARES). Biology Direct 2015, 10:41.
  • Bernet GP, Muñoz-Pomer A, Dominguez-Escriba L, Covelli L, Bernad L, Ramasamy S, Futami R, Sempere JM, Moya A and Llorens C. 2011. GyDB Mobilomics: LTR retroelements and integrase-related transposons of the Pea aphid Acyrthosiphon pisum genome. Mobile Genetic Elements 1(2), 0-1. 1-7-2011. Landes Bioscience.
  • Covelli L, Muñoz-Pomer A, Dominguez-Escriba L, Futami R, Bernet GP, Moya A and Llorens C. 2011. The GyDB collection is now publicly available within the Gypsy Database of Mobile Genetic Elements. Biotechvana bioinformatics:2011-CR1
  • Muñoz-Pomer A, Futami R, Sempere JM, Moya A, and Llorens C. 2011. CheckAlign 2.0. Biotechvana Bioinformatics: 2011-SOFT1.
  • Muñoz-Pomer A, Futami R, Covelli L, Domínguez-Escribà L, Bernet GP, Sempere JM, Moya A, and Llorens C. 2011. TIME: a sequence editor for the molecular analysis of large DNA and protein sequence samples. Biotechvana Bioinformatics: 2011-SOFT2.
  • Futami R, Muñoz-Pomer A, Viu JM, Dominguez-Escribá L, Covelli L, Bernet GP, Sempere JM, Moya A, Llorens C. GPRO: the professional tool for management, functional analysis and annotation of omic sequences and databases (2011) Biotechvana Bioinformatics: 2011-SOFT3
  • Llorens C, Futami R, Covelli L, Dominguez-Escriba L, Viu JM, Tamarit D, Aguilar-Rodríguez J, Vicente-Ripolles M, Fuster G, Bernet GP, Maumus F, Munoz-Pomer A, Sempere JM, Latorre A, and Moya A. 2011. The Gypsy Database (GyDB) of mobile genetic elements: release 2.0 Nucleic Acids Research (NARESE) 39 (suppl 1): D70-D74 doi: 10.1093/nar/gkq1061
  • Llorens C, Futami R, Renaud G, and Moya A. 2009. Bioinformatic Flowchart and Database to Investigate the Origins and Diversity of Clan AA Peptidases. Biology Direct, 4:3
  • Llorens C, Muñoz-Pomer A, Futami R, and Moya A. 2009. The GyDB Collection of Viral and Mobile Genetic Element Models. In Biotechvana Bioinformatics, CR: GyDB collection V2
  • Llorens C, Futami R, Bezemer D and Moya A. 2008. The Gypsy Database (GyDB) of mobile genetic elements. Nucleic Acids Research (NAR) 36 (Database Issue):38-46
  • Llorens C, Futami R, Muñoz-Pomer A, Vicente-Ripolles M, and Moya A. 2008. Introducing Biotechvana Bioinformatics. In Biotechvana Bioinformatics, Intro
  • Llorens C, Futami R, Vicente-Ripollés M, and Moya A. 2008. The CheckAlign logo-maker application in analyses of both gapped and ungapped DNA and protein alignments. In Biotechvana Bioinformatics, SOFT:CheckAlign
  • Llorens C, Futami R, Vicente-Ripollés M, and Moya A. 2008. Phylograph: A multifunction java editor for handling phylogenetic trees. In Biotechvana Bioinformatics, SOFT: Phylograph
  • Llorens C, Futami R, and Moya A. 2008. The GyDB collection: Ty3/Gypsy and Retroviridae LTR retroelements and related nonviral proteins. In Biotechvana Bioinformatics, CR:GyDB collection
  • Futami R, Llorens C, Vicente-Ripollés M, and Moya A. 2008. The GyDB Package 1.0. In Biotechvana Bioinformatics, DU: GyDB Package
  • Llorens C, Vicente-Ripollés M, and Moya A. 2008. The Join Alignments Server version 1.0. In Biotechvana Bioinformatics, SCR:JAS
  • Llorens C, Vicente-Ripollés M, and Moya A. 2008. The Alignment Format Converter Server 1.0 In Biotechvana Bioinformatics SCR: AFC
  • Llorens C, Futami R, Vicente-Ripolles M, and Moya A. 2008. Biotechvana Search Engine 1.0. In Biotechvana Bioinformatics DU:BSE
  • Futami R, Llorens C, and Moya A. 2008. Biotechvana Queue Manager 1.0. In Biotechvana Bioinformatics, DU:BQM
  • Llorens C, Vicente-Ripollés M, and Moya A. 2008. RMXSC server 1.0. In Biotechvana Bioinformatics, SCR: RMXSC



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    Email: biotechvana(at)biotechvana.com

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    Hipra Scientific S.L.U, Polypeptide Therapeutic Solutions S.L., Biotechvana S.L. and Nostrum Biodiscovery constitute the consortium of enterprises participating in the project "Research of a new vaccine for a human respiratory disease", granted by the CDTI (Center for Industrial Technological Development), and supported by the Ministry of Science and Innovation and financed by the European Union – NextGenerationEU. The main objective of this project is to design a safe immunogenic and effective vaccine against the respiratory syncytial virus.

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